Asia Pacific Vascular Biology Organization Conference 2019

Navigator

Conference Program

May 9-12, 2019
State Key Laboratory of Ophthalmology
Zhongshan Ophthalmic Center, Sun Yat-sen University
Jinsui Road 7, Pearl river new city, Guangzhou, China

May 9, 2019

Opening Ceremony

05:00-05:40 PM
Welcome reception (with snacks)
05:40-06:10 PM
Opening ceremony
06:10-06:20 PM
Yizhi Liu (ZOC, China): Opening remark
06:20-06:30 PM
APVBO Award

Scientific Session

Chairs: Ralf Adams, Xuri Li

06:30-06:55 PM
Peter Carmeliet: Angiogenesis revisited: Role and (therapeutic) implications of endothelial metabolism (KU Leuven, Belgium)
06:55-07:00 PM
Discussion
07:00-07:20 PM
Kairbaan Hodivala-Dilke: Novel methods of tumour growth control by targeting the tumour microenvironment (University of London, UK)
07:20-07:25 PM
Discussion
07:25-07:37 PM
Junhao Hu: Activating NO-sGC pathway in pericytes ameliorates inflammation-induced lung injury (CAS,China)
07:37-07:40 PM
Discussion
07:40-07:52 PM
Weijun Pan: CDS2 Deficiency Converts Outcome of VEGFa Signaling from Angiogenesis to Vascular Regression (CAS,China)
07:52-07:55 PM
Discussion

May 10, 2019

Morning session 1: Vascular Metabolism

Chairs: Ralf Adams, Jaime Grutzendler

08:45-08:57 AM
Luyang Yu: FGFR1 SUMOylation regulates angiogenesis via coordinating endothelial VEGFR2 and NOTCH1 signalings (Zhejiang University, China)
08:57-09:00 AM
Discussion
09:00-09:20 AM
Zoltan Arany: Endothelial Metabolism (University of Pennsylvania, USA)
09:20-09:25 AM
Discussion
09:25-09:45 AM
Mieke Dewerchin: Disruption of the serine synthesis pathway in endothelial cells impairs angiogenesis and compromises neonatal mouse survival (VIB-KU Leuven, Belgium)
09:45-09:50 AM
Discussion
09:50-10:10 AM
Michael Potente: Metabolic regulation of endothelial growth and proliferation (Max Planck Institute for Heart and Lung Research, Germany)
10:10-10:15 AM
Discussion
10:15-10:27 AM
Biao Yan: Non-coding RNA in retinal vascular disease (Fudan University, China)
10:27-10:30 AM
Discussion
Coffee break 15 min

Morning session 2: Vascular Permeability and Stem/Progenitor Cells

Chairs: Napoleone Ferrara, Aimin Xu

10:45-11:05 AM
Rong Wang: Cell Signaling in Arterial Venous Programming and Arteriovenous Malformation (UCSF, USA)
11:05-11:10 AM
Discussion
11:10-11:30 AM
Tatiana V Byzova: Mechanosensing in Retinas and Neurovasculature (Cleveland Clinic, USA)
11:30-11:35 AM
Discussion
11:35-11:55 AM
Lena Claesson-Welsh: The vascular barrier, its composition, dynamics and role in pathologies (Uppsala University, Sweden)
11:55-12:00 PM
Discussion
12:00-12:20 PM
Min Wang: Neurovascular unit stability is critical for CCM initiation and progression (Yale University, USA)
12:20-12:25 PM
Discussion

Kanghong Biotech Satellite Conference (lunch provided)

Chairs: Yizhi Liu (ZOC, SYSU, China), Xiaoling Liang (ZOC, SYSU, China)

12:35-12:40 PM
Yizhi Liu, Xiaoling Liang: Welcome and Introduction (ZOC, SYSU, China)
12:40-12:55 PM
Xuri Li: Inhibition of VEGF-A upregulates other VEGF family members and VEGF receptors (ZOC, SYSU, China)
12:55-13:10 PM
Youxin Chen: The Path to PANDA: Conbercept Development and Clinical Trials (Peking Union Medical College Hospital, China)
13:10-13:25 PM
Su Chen: Current Angiogenesis Biologics Development in China (Kanghong Biotech., China)
13:25-13:35 PM
Yizhi Liu, Xiaoling Liang: Discussion and Summary (ZOC, China)

Afternoon session 1: Vascular Signaling

Chairs: Bin Zhou, Timothy Hla

13:45-14:00 PM
Group photo in front of the main entrance of the SKLO building
14:00-14:20 PM
Hong Chen: Molecular Mechanisms of Endocytic Adaptor Switch Controlling Angiogenic Signaling (Boston Children's Hospital, USA)
14:20-14:25 PM
Discussion
14:25-14:45 PM
Jan Kitajewski: CLICs: Metamorphic proteins linking endothelial GPCRs to Rho GTPases (University of Illinois, USA)
14:45-14:50 PM
Discussion
14:50-15:10 PM
Michael Simons: Selective control of vascular permeability (Yale, USA)
15:10-15:15 PM
Discussion
15:15-15:27 PM
Jincai Luo: A new signaling axis in regulating cAMP-mediated endothelial exocytosis critical for vascular thrombosis and bleeding (Peking University, China)
15:27-15:30 PM
Discussion
Coffee break 15 min

Afternoon session 2: Lymphatic system and Vascular Injury

Chairs: Jennifer Gamble, Hellmut Augustin

15:45-16:05 PM
Jalees Rehman: Endothelial Heterogeneity in Vascular Injury and Regeneration (University of Illinois, USA)
16:05-16:10 PM
Discussion
16:10-16:30 PM
Kari Alitalo: Translational insights to vascular growth factors (University of Helsinki, Finland)
16:30-16:35 PM
Discussion
16:35-16:55 PM
Ben Hogan: Constraint of vascular Erk signaling by a pre-mRNA splicing mechanism limits lymphatic specification during development (University of Queensland, Australia)
16:55-17:00 PM
Discussion
17:00-17:20 PM
Tatiana Petrova: Mechanisms of lymphatic vessel specialization (University of Lausanne, Switzerland)
17:20-17:25 PM
Discussion
17:25-17:45 PM
Alex F Chen: Innate immunity and vascular injury (University of Pittsburgh, USA)
17:45-17:50 PM
Discussion

May 11, 2019

Morning session 1: Neural-Vascular Link and Vascular Regulation

Chairs: Zoltan Arany, Michael Potente

08:45-08:57 AM
Xialin Liu: Microglia: magic cells in retinal angiogenesis (ZOC, SYSU, China)
08:57-09:00 AM
Discussion
09:00-09:20 AM
Yoshiaki Kubota: Cellular and molecular basis of the neurovascular link (Keio University, Japan)
09:20-09:25 AM
Discussion
09:25-09:45 AM
Didier Stainier: Early vascular development in zebrafish and mouse (Max Planck Institute for Heart and Lung Research, Germany)
09:45-09:50 AM
Discussion
09:50-10:10 AM
Karina Yaniv: Endothelial cell differentiation and formation of organ-specific vessels (Weizmann Institute of Science, Israel)
10:10-10:15 AM
Discussion
10:15-10:35 AM
Xuri Li: VEGF-B: the Yin and Yang in angiogenesis (ZOC, SYSU, China)
10:35-10:40 AM
Discussion
Coffee break 15 min

Morning session 2: Tumor Angiogenesis and Vascular Inflammation

Chairs: Tatiana V Byzova, Mieke Dewerchin

10:55-11:15 AM
Yihai Cao: Antiangiogenic cancer therapy: mechanistic challenges and clinical implications (Karolinska Institute, Sweden)
11:15-11:20 AM
Discussion
11:20-11:40 AM
Hellmut Augustin: Molecular Analysis of Tumor-Vessel Interactions during Tumor Progression and Metastasis (Heidelberg University, Germany)
11:40-11:45 AM
Discussion
11:45-12:05 PM
Asrar B. Malik: Endothelial Sensing of DNA and Vascular Inflammation (University of Illinois, USA)
12:05-12:10 PM
Discussion
12:10-12:22 PM
Jia Li: Low fluid shear stress conditions contribute to activation of cerebral cavernous malformation signalling pathways
12:22-12:25 PM
Discussion

Berry Genomics Corporation, Satellite Conference (lunch provided)

Chairs: Xuri Li (ZOC, China)

12:25-12:37 PM
Desheng Xu: Resolving biological questions from multiple angles with 10x Genomics (Berry Genomics Corporation)

Afternoon session 1: Vascular Diseases and Endothelial Specialization

Chairs: Lena Claesson-Welsh, Michael Simons

14:00-14:20 PM
Yuping Yuan: Microvascular dysfunction and gut ischemia reperfusion injury (University of Sydney, Australia)
14:20-14:25 PM
Discussion
14:25-14:37 PM
Jing Li: Critical role of mechanosensitive ion channel protein Piezo1 in vascular biology (Guangzhou University of Chinese Medicine, China)
14:37-14:40 PM
Discussion
14:40-15:00 PM
Timothy Hla: Transcriptional gradients in angiogenesis (Boston Children's Hospital, USA)
15:00-15:05 PM
Discussion
15:05-15:22 PM
Jennifer Gamble: The Ageing Endothelium (Centenary Institute, Australia)
15:22-15:25 PM
Discussion
15:25-15:42 PM
Bin Zhou: Genetic evidence of Sca1+ vascular stem cells for smooth muscle regeneration (CAS, China)
15:42-15:45 PM
Discussion
Coffee break 15 min

Afternoon session 2: New Advances in Vascular Research

Chairs: Tatiana Petrova, Jan Kitajewski

16:00-16:20 PM
Aimin Xu: Perivascular adipose tissues in the Regulation of Vascular Homeostasis (University of Hong Kong, HK, China)
16:20-16:25 PM
Discussion
16:25-16:45 PM
Ralf H. Adams: Regulation of stem and progenitor cell function by the bone vasculature (Max Planck Institute for Molecular Biomedicine, Germany)
16:45-16:50 PM
Discussion
16:50-17:10 PM
Jaime Grutzendler: In vivo optical interrogation of neurovascular regulation and pathology (Yale, USA)
17:10-17:15 PM
Discussion
17:15-17:35 PM
Napoleone Ferrara: New insights in intraocular angiogenesis (UC San Diego Moores Cancer Center, USA)
17:35-17:40 PM
Discussion

May 12, 2019

Departure